TotalPackage
TESTing the waters
- Joined
- Aug 11, 2023
- Messages
- 5
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Found this interesting video of the man himself, Peter Janoshik, discussing peptide handling, dissolving, storing, stability etc.
See here:
Key discussion points from the interview include:
See here:
Key discussion points from the interview include:
- Test Efficacy and Failure Rates
- Peter considers heavy metal testing "useless".
- Sterility tests fail relatively often, around 3-5% of the time.
- Endotoxin failures are rare, and usually occur in liquid products that also fail sterility tests.
- Peptide Handling Myths Peter debunks the myth that peptides are extremely sensitive to shaking or rapid water injection, stating it was perpetuated by sellers of low-quality growth hormone. He confirms that peptides can be shaken and water can be injected directly onto the powder.
On the method of reconstitution (sterile water, sterile 0.9% NaCl or BAC water) he states that all three are about equal, though he would recommend saline if your peptide dissolves cleanly in it since it will have the least chance of inducing an injection site reaction. - Peptide Shelf Life and Storage Peptides, especially properly made, undissolved lyophilized vials, are very stable. Peter recounted an instance where human growth hormone stored at room temperature for a decade in his garage was still mostly effective, albeit slightly degraded. He advises storing peptides in a fridge for years or a freezer for decades.
- Reconstituted Peptide Shelf Life Reconstituted peptides can last longer than commonly believed, but the main concern after 2-4 weeks is microbial contamination, not degradation of the active compound. He recommends using vials sized appropriately for weekly doses to avoid issues.
- He states that peptides in reconstituted vials "might maintain close to full efficacy for 6-8 weeks", which is something important to add in addition to his own personal recommendation of not going over a month on a vial due to the potential for contamination.
- Bacteriostatic Water (BAC Water) Peter expresses concern about generic BAC water, noting instances of zero benzyl alcohol content and concerning endotoxin results. He suggests using sterile water or saline for reconstitution, especially pharmacy-grade options.
- Overall Failure Rate Janoshik's overall failure rate for peptides (considerably different dosage, wrong peptide, or no peptide) is roughly 5%.